2025 Realistic Latest ACRP-CP Test Simulator Help You Pass ACRP-CP Easily
2025 Realistic Latest ACRP-CP Test Simulator Help You Pass ACRP-CP Easily
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Tags: Latest ACRP-CP Test Simulator, ACRP-CP Valid Exam Experience, ACRP-CP Exam Reviews, New ACRP-CP Test Answers, Valid ACRP-CP Exam Test
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ACRP Certified Professional Exam Sample Questions (Q113-Q118):
NEW QUESTION # 113
An impartial witness should be present during the entire informed consent discussion when:
- A. A parent/guardian is consenting for a minor subject.
- B. A subject has been determined to be vulnerable.
- C. A legally acceptable representative is unable to read.
- D. An interpreter is translating the consent form for a subject.
Answer: C
Explanation:
An impartial witness is required when a legally acceptable representative (LAR) or the subject themselves cannot read. The witness ensures that the information is presented accurately and that the consent process is conducted ethically. The witness also signs the consent form to confirm that the subject or representative understands the study details.
GCP guidelines require an impartial witness to be present to confirm that the consent information is correctly conveyed and understood when the subject or LAR cannot read.
"An impartial witness is required when the subject or legally acceptable representative is unable to read, ensuring the consent process is transparent and ethically sound." Objectives:
* Protect the rights of individuals with literacy challenges.
* Maintain ethical standards in the consent process.
NEW QUESTION # 114
AEs that occur between study visits of a clinical trial should be evaluated by the:
- A. Principal Investigator
- B. Medical monitor
- C. Study pharmacovigilance physician
- D. Subject's primary care physician
Answer: A
Explanation:
The Principal Investigator (PI) is responsible for evaluating Adverse Events (AEs) that occur between study visits. The PI must assess the severity, causality, and potential relationship to the investigational product (IP).
Proper evaluation ensures that any necessary medical interventions are promptly administered and that relevant information is recorded and reported accurately.
GCP guidelines specify that the PI is accountable for the medical care of trial subjects, including evaluating AEs and ensuring their safety.
"The PI must evaluate any adverse events occurring between study visits to determine their relevance to the investigational product and manage patient care." Objectives:
* Ensure prompt and accurate evaluation of AEs.
* Maintain the safety and well-being of study participants.
NEW QUESTION # 115
Who is responsible for defining, establishing, and allocating all trial-related duties and functions prior to initiating a trial?
- A. Sponsor
- B. CRO
- C. IRB/IEC
- D. Investigator
Answer: A
Explanation:
The sponsor is responsible for defining, establishing, and allocating all trial-related duties and functions before the trial begins. This includes outlining roles and responsibilities in collaboration with investigators, CROs, and other stakeholders. Proper delegation ensures the trial is conducted according to protocol and regulatory requirements.
This answer is verified based on GCP guidelines, which clearly state that sponsors are responsible for the organization and management of trial-related tasks.
"The sponsor is responsible for allocating duties and functions related to the conduct of the trial, ensuring compliance with regulatory and ethical standards." Objectives:
* Clarify the sponsor's role in clinical trial management
* Define responsibilities in trial planning
NEW QUESTION # 116
Per protocol, participants are scheduled to receive IP, which is calculated based on the participant's current weight. Unknown to the pharmacist, a participant recently lost 15 pounds and was overdosed as a result. What is the FIRST action the CRC must take to ensure the participant's safety?
- A. Notify the PI.
- B. Notify the sponsor.
- C. Call the participant to return for an unscheduled visit.
- D. Report a protocol deviation to the IRB/IEC.
Answer: A
Explanation:
The CRC's first responsibility is to immediately inform the Principal Investigator (PI), who is responsible for the participant's medical care. The PI will assess the situation, determine the potential risk, and initiate appropriate clinical actions to ensure the participant's safety. This may include medical evaluation or adjusting the dosing regimen.
According to GCP guidelines, any issue that may affect participant safety should be promptly communicated to the PI to ensure appropriate medical management.
"The investigator must be informed immediately of any events that could compromise participant safety, allowing for prompt clinical decision-making." Objectives:
* Ensure rapid response to dosing errors.
* Maintain participant safety as a priority.
NEW QUESTION # 117
Centralized monitoring can:
- A. Enable appropriate stratification of subject enrollment.
- B. Identify IP accountability and storage issues.
- C. Indicate the need to send monitors to perform onsite visits.
- D. Confirm why sites are deviating from the protocol.
Answer: C
Explanation:
Centralized monitoring involves the remote evaluation of data trends, outliers, and inconsistencies across sites. If significant issues are identified through centralized monitoring, it may prompt the need for targeted on-site visits to investigate and resolve the identified issues. This approach optimizes resource utilization and focuses on potential problem areas.
GCP guidelines support the use of centralized monitoring to identify risks that warrant on-site monitoring, promoting efficient and targeted oversight.
"Centralized monitoring can identify data patterns or anomalies that indicate the need for an on-site visit to verify and address the issue." Objectives:
* Enhance monitoring efficiency through data-driven decisions.
* Prioritize on-site visits based on identified risks.
NEW QUESTION # 118
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